TRPS1 MODULATES CHROMATIN ACCESSIBILITY TO REGULATE ESTROGEN RECEPTOR ALPHA (ER) BINDING AND ER TARGET GENE EXPRESSION IN LUMINAL BREAST CANCER CELLS.

Common genetic variants in the repressive GATA-family transcription factor (TF) TRPS1 locus Golf Towel are associated with breast cancer risk, and luminal breast cancer cell lines are particularly sensitive to TRPS1 knockout.We introduced an inducible degron tag into the native TRPS1 locus within a luminal breast cancer cell line to identify the di

The avionics network supports high-safety-level flight operations, with the analysis of transmission failures serving as a crucial means for its safety evaluation.Due to the time-dependent nature of the failure probability in avionics networks, traditional constant and unchangeable probability values can deviate from the actual situation under spec

Abstract Background A 34-year-old gentleman presented with Staphylococcus salivarius infective endocarditis 13 years after aortic homograft and mitral valve repair for degenerative bicuspid aortic valve associated with rheumatic heart disease.The homograft had calcified, and the mitral repair had deteriorated with severe regurgitation.Multidiscipli

Plastic metalization process is carried out by heating the aluminum to its melting point in a vacuum so that the atoms and molecules will be evaporate and stick on to the plastic surface, then forming thin layer accross its surface.PT.Tomoko Daya Perkasa is one of the companies High Chairs who performs plastic metalization.In doing this process, th